Toxic Effects of Arsenic in Commercially Important Fish Rohu Carp, Labeo rohita of Bangladesh

This study was designed to elucidate the effects of arsenic (As) on morpho-behavior, growth development and molecular mechanisms a commercially important fish, rohu carp, Labeo rohita, in Bangladesh. Fish fry with an average weight 387.5 ± 169.25 mg length 3.35 0.37 cm were collected from local hatchery Mymensingh, Bangladesh acclimatized for week Department Fisheries, University Dhaka before starting exposure arsenic. Fishes exposed period 14 days three treatments NaAsO2, namely treatment 1(T1)—2.5 mg/L; 2 (T2)—15 3 (T3)—30 mg/L, along control (C)—0.0 replicates. These concentrations determined based LC50 value 96 h measured this experiment. revealed remarkable morphological abnormalities deformities arsenic-exposed carp. In fish 30 caudal fin erosion frequent deformity. There no significant difference RNA:DNA ratio among treatments. The overall decreased as concentration increased. T3 had statistically negative gain (?0.05 0.07 g), but other (T1 T2) gain. Different types histopathological changes observed gills intestines arsenic-treated fish. Necrosis severe damages found secondary lamellae at highest (30 mg/L). Epithelial lifting, irregular shape gill raker also primary same treatment. study, expression heat shock protein (HSP 60) metallothionein (MT) genes assessed by qPCR, these upregulated different compared controls. findings present suggest that pollution significantly morphology, behavior, growth, development, histopathology economically